Welcome to this month’s edition of The Avané Edit. At Avané, every treatment is rooted in science — but it’s the stories, results, and expert care that truly bring our work to life. This month, we’re diving into everything from cutting-edge laser technology to the real talk around weight loss journeys. Whether you’re looking for trusted advice, behind-the-scenes glimpses, or a sign to finally book that facial — consider this your curated roundup of what’s trending, what’s working, and what’s next in skin health and aesthetics.
Welcome to the future of dermatology and medicine.
Good skin isn’t a filter, it’s a function.
At Avané, we help tissue remember how to heal. That means cell-level signals, plans that fit Nairobi life, and techniques that respect melanin.
No drama, just method.
We start with detailed history-taking, followed by a thorough examination and a clear diagnosis, then build a tailor-made program just for you.
Then we sequence with intent: Prepare the field. Deliver the right signals. Protect the barrier. Add energy only when structure needs it.
Stem-cell protocols are screened and prepared under strict handling and then administered precisely for medical or aesthetic purposes.
This is breadth with a purpose, not a pile of tools.
A) Mesenchymal stem cells, MSC (/meh-ZEN-kih-muhl/)
We use perinatal-sourced MSC signaling in select dermatology cases. The goal is not to replace your cells. It is to guide them. MSC release a pro-healing secretome of cytokines, growth factors, and exosomes that helps calm inflammation and organize repair.
Evidence from joint programs shows improvements in pain and function in knee osteoarthritis when done under specialist oversight, which supports the broader biologic logic of MSC-guided care.
We do not use MSC in active cancer, and oncology clearance is required for survivors or patients on chemotherapy. Autoimmune cases are coordinated with the treating team.
Study snapshots
B) Bone marrow route, Miracell-type system (BMAC) (/MY-ruh-cell/)
What it is ?
A bone-marrow aspirate concentrate prepared on a closed, sterile system. It contains marrow-derived regenerative components and growth factors. This is a different route from the perinatal MSC approach above. BMAC has been explored in orthopedics and sports medicine, with several reviews reporting short- to mid-term pain and function gains. It remains an evolving field that requires careful selection and measured expectations.
C) Adipose stem-cell micro-grafts, Regenera Activa (/reh-JEN-er-uh/)
What it is?
A tiny adipose sample is processed into regenerative micro-grafts, then placed where support is needed, most often the scalp in early thinning. The aim is to settle shedding and nudge follicles back into a healthy cycle. Clinical series report improvements in density and thickness within two to three months in suitable candidates. The platform originates in
Europe and is now part of the Remedi group that includes the Italian Rigenera technology.
How we combine
We often pair Regenera with PRP for extra growth-factor support, then layer maintenance based on dermoscopy photos and response.
Study snapshots
Exosomes are nano-sized packets that carry proteins and RNA. They are messages. We place them after controlled procedures such as microneedling or RF so the signals reach the right depth. Patients often report quicker calming and smoother surface within days, then refinement across two to four sessions.
What the literature says
Modern reviews in dermatology and skin biology line up on four jobs exosomes can help with during wound repair:
Burns & thermal injury (what’s different)Burns are hard to heal: they’re inflamed, oxidatively stressed, and slow to close. Reviews in regenerative medicine show exosomes helping burn wounds close faster and grow healthier blood supply. When exosomes are mixed into hydrogels or scaffolds (think: a long-acting dressing), the messages stay in place longer and push healing toward smoother, less contracted scars.
Translation: fewer contractures, better pliability, smoother collagen architecture in animal data; clinical trials are just beginning. BioMed Central
Hypertrophic scars & keloids (the fibrosis problem)In scars that “overbuild,” the goal is to slow the overactive fibroblasts and stop extra collagen from piling up. Lab and animal work with fat-derived (ADSC) exosomes shows they can:
Result: thinner, more flexible scars in preclinical models.
Study snapshots
We draw a small tube of blood and concentrate the platelets. Those platelets carry growth factors that activate fibroblasts and support repair in skin or hair.
Where it helps
Undereye quality. Acne scars. Early hair thinning. In scars, results are stronger when PRP is paired with microneedling or fractional energy. In hair, multiple reviews support PRP as a helpful option for androgenetic alopecia when done as a series.
Study snapshots
Culture note
PRP hit mainstream after the “vampire facial” moment. The lesson is not celebrity. It is comfort planning and sterile technique. The evidence lives in the data above.
Polynucleotides are purified DNA fragments, often from salmon sperm. They cue fibroblasts to hold water and rebuild structure. We reach for PD when under-eyes look crepey, necks look papery, or skin is reactive and tired. Human studies report gains in elasticity, hydration, and fine lines in delicate zones. Product quality and technique matter.
Study snapshots
Mesogun as main delivery
For even, cell-friendly placement of PRP or supportive solutions across scalp and large fields, we use French mesotherapy injectors, including the U225 Mesogun and a UTT05-class system. These maintain consistent droplet size and depth, so growth factors and signals are distributed uniformly. The U225 is a CE-marked injector designed and assembled in France, built for high-frequency, precise intradermal delivery. Sessions are virtually painless, don’t require numbing cream, and have no downtime.
Why this matters for melanin-rich skin
Uniform depth reduces hot spots and lowers the risk of post-inflammatory pigment change. It also keeps comfort steady, which helps patients complete their series.
ABMI, explained
ABMI here refers to AI-based mole imaging and total-body photography used in skin-cancer surveillance. These systems compare images over time and flag change that needs a clinician’s eye. They do not diagnose cancer on their own. They focus attention so a trained dermatologist can act early. We keep oncology safety front-and-center. If a patient is in active cancer care, regenerative therapies wait. If a survivor is ready for skin support, we coordinate timing with the oncology team.
Why it belongs in a regenerative clinic
Regeneration is long-horizon care. Cancer screening education belongs in that horizon. We teach ABCDE warning signs, sun behavior in Nairobi, and the value of serial photos.
Yes. We tailor needle depth, intervals, and any energy settings for Fitzpatrick IV to VI, and we protect the barrier.
Most plans run three to six appointments, then maintenance based on goals and response.
PRP glow in two to three weeks. Exosome calm in days. Polynucleotide softness in about a week. MSC-guided plans and hair programs build across months.
Yes. We sequence rather than stack, so skin responds cleanly.
We’re Here
At Yaya. At Gigiri. On WhatsApp. On email.
In person where the real shift begins.
This isn’t about chasing numbers on a scale. It’s about feeling like you again.
